Websites which use frames are not seo friendly.
Disadvantages of frames
1.Search engines treat frames as hyper links to other pages, so if for example they manage to spider the frame containing your menu, they pages they index will be indexed but without the surrounding frames. If someone finds one or your pages on a search engine they will not be able to navigate around your site.
2.The most important disadvantage is that it is difficult to link to a particular page on your site other than the page containing the frames (usually the homepage) - this is a big disadvantage if you use email to market your site and you want to link to different parts of your web site.
Source: The webs eye